师资队伍

吕鑫

博士 ,教授,硕士生导师、博士生导师

邮箱:lvxin@sxu.edu.cn

研究方向:荧光染料、探针、光动力诊疗试剂的开发及生物应用

个人简介

吕鑫,博士,四级教授,博士生导师,山西省高等学校优秀青年学术带头人,“三晋英才”(青年人才),山西大学化学化工学院化学系主任,光化学功能分子山西省重点实验室副主任。主要研究方向为荧光染料、探针、光动力诊疗试剂的开发及生物应用。
近年来,先后主持国家自然科学基金面上项目1项、青年项目1项、省部级项目3余项;Chem. Comm.、Sens. Actuators B.、Biomaterials.、Analyst.等国际国内重要学术刊物上发表学术论文20余篇;获山西省科技进步二等奖1项(排名第二);授权发明专利2项;主讲本科生课程《高分子化学》、《高分子化学实验》。

学术论文

[1] Minghao Ren, Chengyong Zhou, Linfang Wang, Xin Lv*, Wei Guo. Rationally designed meso-benzimidazole-pyronin with emission wavelengthbeyond 700 nm enabling in vivo visualization of acute-liver-injury-inducedperoxynitrite. Chinese Chemical Letters. 2023, 34, 107646
[2] Xin Lv, Taihe Han, Yi Wu, Boran Zhang, Wei Guo*. Improving the fluorescence brightness of distyryl Bodipys by inhibiting the twisted intramolecular charge transfer excited state, Chem. Comm., 2021, 57, 9744-9747.
[3] Xin Lv, Chunmei Gao, Taihe Han, Hu Shi and Wei Guo*.Improving the quantum yields of fluorophores by inhibiting twisted intramolecular charge transfer using electron-withdrawing group-functionalized piperidine auxochromes. Chem. Comm., 2020, 56, 715-718.
[4] Xin Lv, Taihe Han, Xia Yuan, Hu Shi, Wei Guo*. Design, synthesis, and bioimaging applications of a new class of carborhodamines, Analyst, 2021, 146, 64-68.
[5] Xin Lv, Xia Yuan, Yue Wang and Wei Guo*. A naphthalimide based fast and selective fluorescent probe for hypochlorous acid/hypochlorite and its application for bioimaging. New J. Chem., 2018, 42, 15105-15110.
[6] Minghao Ren, Linfang Wang, Xin Lv*, Jing Liu, Hu Chen, Juanjuan Wang and Wei Guo*. Development of a benzothiazole-functionalized red-emission pyronin dye and its dihydro derivative for imaging lysosomal viscosity and tracking endogenous peroxynitrite. J. Mater. Chem. B, 2019, 7, 6181-6186.
[7] Yue Wang, Yawei Liu, Junfeng Miao, Minghao Ren, Wei Guo, Xin Lv*. A novel Bodipy-based fluorescent probe for Au3+ ions with high selectivity and its application to bioimaging [J]. Sensors and Actuators B, 2016, 226, 364-369.
[8] Yue Wang, Xin Lv*, Wei Guo*. A reaction-based and highly selective fluorescent probe for hydrogen sulfide [J]. Dyes and Pigments, 2017, 139, 482-486.
[9] Junfeng Miao#, Yingying Huo#, Xin Lv#, Zhe Li, Hualiang Cao, Heping Shi, Yawei Shi, Wei Guo*. Fast-response and highly selective fluorescent probes for biological signaling molecule NO based on N-nitrosation of electron-rich aromatic secondary amines [J]. Biomaterials, 2016, 78, 11-19.
[10] Xin Lv, Yue Wang, Song Zhang, Yawei Liu, Jian Zhang and Wei Guo*, A specific fluorescent probe for NO based on a new NO bingding Group [J]. Chem.Comm., 2014, 7499-7502.

科研项目

[1].碳-罗丹明及羰基-罗丹明近红外荧光染料的构建及其生物应用研究.国家自然科学基金面上项目,2018.01-2021.12,主持人
[2].1331优秀青年学术带头人支持计划. 2018.06-2021.06,主持人
[3].一氧化氮荧光探针的构建及其生物细胞成像应用.国家自然科学基金青年项目,2014.01-2016.12,主持人
[4].生物信使分子硫化氢荧光探针的构建及其生物细胞成像应用.山西省基础研究计划青年项目,2014.01-2016.12,主持人
[5],有机小分子荧光探针的构建及其生物传感研究.山西省高等学校科技创新项目,2013.07-2015.07,主持人