郭炜，男，1972年生，博士，二级教授，博士生导师。现任山西大学化学化工学院党委书记，兼任山西省化学会理事长、中国化学会理事、中国感光学会光化学与光生物专业委员会委员、山西省精准医疗与伴随诊断专业委员会副主委、光转换功能分子山西省重点实验室主任、山西省科技创新人才团队—领军团队—带头人。入选教育部新世纪优秀人才、山西省学术技术带头人等人才计划。主要从事荧光传感与光动力治疗研究，迄今在Chem. Soc. Rev.、J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、Coord. Chem. Rev.、Chem. Sci.、Biomaterials等国际权威期刊发表学术论文80余篇，他引5000余次；获批中国发明专利6项；主持国家自然科学基金7项、中央引导地方科技发展资金项目1项；获山西省科学技术二等奖2 项、山西省教学成果特等奖1项、一等奖2项。
[1] Zhen Yang, Jing Liu,* Hongxing Zhang, Mengxing Liu, Meixin Liu, Yanrong Li, Yuan-Qiang Sun,* Wei Guo,* Conformationally restrained coumarin hemicyanines: Improved quantum yields and potential applications in bioimaging and photodynamic therapy, Sensors & Actuators: B. Chemical 2023, 387, 133832.
[2] Yuanqiang Sun, Pengjuan Sun, Zhaohui Li*, Lingbo Qu and Wei Guo*, Natural flavylium-inspired far-red to NIR-II dyes and their applications as fluorescent probes for biomedical sensing, Chem. Soc. Rev., 2022, 51, 7170-7205.
[3] Junfeng Miao, Yingying Huo,* Guangxiao Yao, Yu Feng, Jiajin Weng, Wei Zhao, and Wei Guo*, Heavy Atom-Free, Mitochondria-Targeted, and Activatable Photosensitizers for Photodynamic Therapy with Real-Time In-Situ Therapeutic Monitoring, Angew. Chem. Int. Ed., 2022, e202201815.
[4] Xin Lv,* Taihe Han, Yi Wu, Boran Zhang and Wei Guo*, Improving the fluorescence brightness of distyryl Bodipys by inhibiting the twisted intramolecular charge transfer excited state, Chem. Commun., 2021, 57, 9744–9747.
[5] Jing Liu, Mengxing Liu, Hongxing Zhang, and Wei Guo*, High-Contrast Fluorescence Diagnosis of Cancer Cells/Tissues Based on b-Lapachone-Triggered ROS Amplification Specific in Cancer Cells, Angew. Chem. Int. Ed., 2021, 60, 12992–12998.
[6] Yuanqiang Sun, Pengjuan Sun, and Wei Guo*, Fluorescent probes for iron, heme, and related enzymes, Coord. Chem. Rev., 2021, 429, 213645.
[7] Xin Lv, Taihe Han, Xia Yuan, Hu Shi and Wei Guo*, Design, synthesis, and bioimaging applications of a new class of carborhodamines, Analyst, 2021, 146, 64–68.
[8] Hongxing Zhang, Jing Liu,* Yuan-Qiang Sun, Mengxing Liu, and Wei Guo*, Carbon-Dipyrromethenes: Bright Cationic Fluorescent Dyes and Potential Application in Revealing Cellular Trafficking of Mitochondrial Glutathione Conjugates, J. Am. Chem. Soc., 2020, 142, 17069−17078.
[9] Xin Lv, Chunmei Gao, Taihe Han, Hu Shi and Wei Guo*, Improving the quantum yields of fluorophores by inhibiting twisted intramolecular charge transfer using electron-withdrawing group-functionalized piperidine auxochromes, Chem. Commun., 2020, 56, 715−718.
[10] Jing Liu, Mengxing Liu, Hongxing Zhang, Xuehong Wei, Juanjuan Wang, Ming Xian* and Wei Guo*, Exploring cysteine regulation in cancer cell survival with a highly specific “Lock and Key” fluorescent probe for cysteine, Chem. Sci., 2019, 10, 10065–10071.
[11] Yingying Huo, Junfeng Miao, Junru Fang, Hu Shi, Juanjuan Wang, and Wei Guo*; Aromatic secondary amine-functionalized fluorescent NO probes: improved detection sensitivity for NO and potential applications in cancer immunotherapy studies; Chem. Sci., 2019, 10, 145–152.
[12] Junfeng Miao, Yingying Huo, Hu Shi, Junru Fang, Juanjuan Wang, and Wei Guo*; A Si-rhodamine-based near-infrared fluorescent probe for visualizing endogenous peroxynitrite in living cells, tissues, and animals; J. Mater. Chem. B, 2018, 6, 4466–4473.
[13] Hongxing Zhang, Jing Liu, Bo Hu, Linfang Wang, Zhen Yang, Xu Han, Juanjuan Wang, Wei Bai, and Wei Guo*; Dual-Channel Fluorescence Diagnosis of Cancer Cells/Tissues Assisted by OATP Transporters and Cysteine/Glutathione; Chem. Sci., 2018, 9, 3209–3214.
[14] Hongxing Zhang, Jing Liu, Linfang Wang, Minjia Sun, Xiaohan Yan, Juanjuan Wang, Jian-Ping Guo, and Wei Guo*; Amino-Si-Rhodamines: a New Class of Two-Photon Fluorescent Dyes with Intrinsic Targeting Ability for Lysosomes; Biomaterials, 2018, 158, 10−22.
[15] Yingying Huo, Junfeng Miao, Lingjun Han, Yaping Li, Zhe Li, Yawei Shi, and Wei Guo*; Selective and Sensitive Visualization of Endogenous Nitric Oxide in Living Cells and Animals by a Si-Rhodamine Deoxylactam-Based Near-Infrared Fluorescent Probe; Chem. Sci., 2017, 8, 6857−6864.
[16] Hongxing Zhang, Jing Liu, Chenlu Liu, Pengcheng Yu, Minjia Sun, Xiaohan Yan, Jian-Ping Guo, Wei Guo*; Imaging lysosomal highly reactive oxygen species and lighting up cancer cells and tumors enabled by a Si-rhodamine-based near-infrared fluorescent probe; Biomaterials, 2017, 133, 60−69.
[17] Junfeng Miao, Yingying Huo, Qian Liu, Zhe Li, Heping Shi, Yawei Shi, and Wei Guo*; A new class of fast-response and highly selective fluorescent probes for visualizing peroxynitrite in live cells, subcellular organelles, and kidney tissue of diabetic rats; Biomaterials, 2016, 107, 33−43.
[18] Junfeng Miao, Yingying Huo, Xin Lv, Zhe Li, Hualiang Cao, Heping Shi, Yawei Shi, and Wei Guo*; Fast-response and highly selective fluorescent probes for biological signaling molecule NO based on N-nitrosation of electron-rich aromatic secondary amines; Biomaterials, 2016, 78, 11-19.
[19] Jing Liu, Yuan-Qiang Sun, Hongxing Zhang, Heping Shi, Yawei Shi, and Wei Guo*; Sulfone-Rhodamines: A New Class of Near-Infrared Fluorescent Dyes for Bioimaging; ACS Applied Materials & Interfaces. 2016, 8, 22953−22962.
[20] Yawei Liu, Xin Lv, Min Hou, Yawei Shi, and Wei Guo*; Selective Fluorescence Detection of Cys over Hcy and GSH Based on a Cys-Triggered Dual Michael Addition/Retro-aza-aldol Cascade Reaction; Anal. Ch
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