师资队伍

魏春英

博士 ,教授,博士生导师

邮箱:weichuny@sxu.edu.cn

研究方向:化学生物学

个人简介

魏春英,博士,三级教授,博士生导师,主要研究方向为纳米酶及其生物医学应用。
先后主持国家自然科学基金面上项目2项、省部级项目10余项;在Biosensors and Bioelectronics、Sensors and Actuators B、Talanta等重要学术期刊发表学术论文60余篇;获山西省科技进步二等奖一项(排名第二);讲授本科生专业基础课《无机化学》、《无机化学实验》,博士研究生专业必修课《无机化学前沿》。

学术论文

[1] Yingchun Wu, Chunying Wei*,Dual-functional fluorescent probe for imaging ROS and hypoxia dynamic in cancer cells,Sensors & Actuators: B. Chemical, 2024, 419: 136417
[2] Chunying Wei*, Lujie Chen,DNA-based FeCuAg nanoclusters with peroxidase-like and GSH depletion activities for toxicity of in vitro cancer cells, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2024, 317:124446.
[3] Chunying Wei*, Huiqing Lin,Hehe Bai, G/Crich ssDNAbased Fe and Cu/Fe nanoclusters with peroxidaselike activity for intracellular ROS production and cytotoxicity applications, Microchimica Acta,2023,190(5): 201.
[4] Yongqiang Kang, Chunying Wei*, A stilbene derivative as dual-channel fluorescent probe for mitochondrial G-quadruplex DNA in living cells, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 278: 121316.
[5] Yongqiang Kang, Chunying Wei*, Highly selective turn-on red fluorescence probes for visualization of the G-quadruplexes DNA in living cells, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 267: 120518.
[6] Baozhu Zhang, Chunying Wei*, The sensitive detection of ATP and ADA based on turn-on fluorescent copper-silver nanoclusters, Analytical and Bioanalytical Chemistry, 2020, 412(11):2529-2536.
[7] Dan Han, Chunying Wei*,A molecular beacon based on DNA-templated silver nanoclusters for the highly sensitive and selective multiplexed detection of virulence genes, Talanta, 2018,181: 24–31.
[8] Chunying Li, Chunying Wei*, DNA-templated silver nanocluster as a label-free fluorescent probe for the highly sensitive and selective detection of mercury ions, Sensors and Actuators B:Chemical,2017,242:563-568.
[9] Chunying Li, Chunying Wei*, DNA-functionalized silver nanoclusters as label-free fluorescent probe for the highly sensitive detection of biothiols and acetylcholinesterase activity, Sensors and Actuators B: Chemical,2017,240:451-458.
[10] Jiaona Xu, Chunying Wei*, The aptamer DNA-templated fluorescence silver nanoclusters: ATP detection and preliminary mechanism investigation, Biosensors and Bioelectronics,2017,87:422-427.

科研项目

[1] 靶向端粒及c-myc G-四链体DNA抗肝癌药物的研发.中央引导地方科技发展资金项目(自由探索类), 2020.01-2021.12,主持。
[2] 靶向G-四股螺旋DNAs抗癌剂的设计、合成,体外生物活性及与DNA键合作用研究.国家自然科学基金面上项目,2012.01-2015.12,主持。
[3] 药物和G-四股螺旋DNA相互作用的激光拉曼光谱和时间分辨荧光光谱研究.国家自然科学基金面上项目,2007.01-2009.12,主持。
[4] 手性分子对G-quadrupex和i-motif的选择性识别.山西省留学基金,2011.07-2013-12,主持。
[5] 人端粒及c-myc G-四链体配体邻菲罗啉衍生物抗HepG2癌细胞增殖的分子机制研究.山西省自然科学基金,2016.07-2018.12,主持。